Rejuran is a regenerative skin treatment derived from salmon DNA polynucleotides (PNs), aiming to assist the skin at a cellular level. It is growing in popularity, partly due to its versatility allows it to be applied to multiple facial and body areas depending on individual concerns, skin type, and age. The following sections outline the key treatment areas, when you might consider your first treatment, and who may benefit.
Rejuran for ageing skin: When to start treatments
Some people choose to take a proactive approach to skin ageing, and Rejuran is increasingly used as a preventative treatment. Early skin changes that results from natural ageing include subtle fine lines, loss of elasticity, and skin dullness, and can manifest as early as your 20’s. Initiating Rejuran treatments at this stage may help maintain skin resilience and delay more visible ageing changes.
Rejuran is proposed to work at the cellular level by stimulating fibroblasts, the cells responsible for collagen production, and supporting extracellular matrix health. Over time, increased fibroblast activity can:
- Improve elasticity and skin firmness
- Reduce subtle texture irregularities
- Increase hydration for a plumper, healthier look
Patients in their late 20s to early 30s often use Rejuran as a preventative measure, while those in their 40s and 50s may combine it with other treatments to address established skin changes that result from ageing.
Rejuran under eye: Who benefits most
Because the under-eye skin is very thin, it is one of the first regions to show fatigue, fine lines, dark circles, and crepiness. Accordingly, choosing the right Rejuran product for the under eyes is vital. Rejuran I (Eye) is specifically formulated for safety around the delicate eye skin. It is softer than standard Rejuran, allowing smooth integration into thin skin without causing lumps or excessive swelling.
Rejuran I is often used to:
- Reduce fine lines and mild crepiness
- Hydrate and improve skin texture
- Subtly diminish dark circles caused by mild skin thinning or poor microcirculation
Suitable candidates typically are those beginning to notice early under-eye changes. Because Rejuran focuses on cellular repair and collagen stimulation, its benefits complement traditional under-eye treatments rather than replacing them, serving as a long-term skin health maintenance tool.
Rejuran for lips: Natural hydration, texture & regeneration
Rejuran may help improve lip quality and hydration without adding volume. Many patients desire hydrated, soft, and smooth lips rather than an increase in size. Rejuran may help achieve this by supporting a healthy extracellular matrix.
Proposed benefits include:
- Natural hydration and plumpness
- Smoother surface texture
- Subtle support for fine lines around the mouth
Unlike lip fillers, Rejuran’s goal is regenerative rather than volumetric. It can be used alone for mild rejuvenation or alongside other methods to refine your lips. Results from Rejuran for the lips are gradual, appearing over weeks as the dermal structure improves.
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Rejuran for acne scars and textural concerns
Patients with mild acne scars or uneven texture may benefit from Rejuran. The treatment encourages fibroblast activity, supports tissue repair, and may help remodel scarred areas.
Unlike resurfacing treatments or lasers that remove outer layers of skin, Rejuran works from within, gradually optimising skin density and elasticity. Over several sessions, patients may notice:
- Smoother skin texture
- Reduced redness and inflammation
- Subtle improvement in shallow scars
For deeper scars, Rejuran is often combined with microneedling or other resurfacing techniques and scar treatments (like subcision) to maximise results. Its regenerative properties make it a low-risk adjunct to more intensive procedures, rather than a primary treatment for scarring.
Rejuran for skin hydration, firming, and radiance
Rejuran can be applied to the full face to optimise hydration, firmness, and overall radiance. By supporting the dermis and stimulating fibroblasts, it aims to strengthen the skin’s internal scaffolding. Possible benefits include:
- Improved softness and suppleness
- Firmer, more elastic skin through collagen stimulation
- A radiant, even complexion
- Smoother skin texcture
Factors Affecting Skin Tightening
While Rejuran is a potential option for skin tightening, the extent of the results may vary depending on several factors, including:
- Age: The severity of skin sagging and the rate of collagen decline will vary with age. Younger individuals may experience more noticeable effects.
- Skin type: Skin type can also influence the results of Rejuran treatment. Individuals with thinner or more delicate skin may see more visible results.
- Lifestyle factors: Things like sun exposure, smoking, and diet can affect skin health and elasticity.
In most cases, Rejuran serves as a secondary option for skin tightening, complementing traditional collagen-stimulating treatments, but it plays a primary role in delicate areas—such as around the eyes—where other treatments are not suitable.
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